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Cognitive Function and Neurodegenerative Disease Glutathione is found in significant concentrations in the brain, where it scavenges free radicals that contribute to neuronal damage

Forms of Administration and Bioavailability Intravenous (IV) Glutathione 1500mg Intravenous administration delivers glutathione directly into the bloodstream, bypassing the digestive system entirely and achieving 100% bioavailability

This enzyme has been reported to present oxidase activity when hydrogen peroxide is absent or levels of H 2 O 2 are low

Not intended for human consumption, injection, or cosmetic use

An open-label study (n=42) found that IV NAC (50 mg/kg) combined with oral NAC (500 mg twice daily) for 3 months increased brain glutathione levels (measured by MRS), increased dopamine transporter binding (measured by DaTscan), and improved UPDRS motor scores (Monti et al., PLoS One, 2016) [53]