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By managing these severe physical symptoms, clonidine makes the detox process far more tolerable, allowing individuals to endure the acute phase with greater comfort

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This cellular energy crisis directly manifests as the profound physical fatigue, "brain fog," and post-exertional malaise (PEM) that patients experience

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Mechanisms may involve enhancement of follicle stem cell activity, improvement of follicle vascularization, and anti-inflammatory effects on the follicle microenvironment