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doi:10.1016/j.freeradbiomed.2018.01.007 157

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Megalin and cubilin receptors at the apical membrane are responsible for endocytosis-mediated reuptake of filtered low-molecular-weight proteins, such as 2-microglobulin (Eshbach and Weisz 2017)

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Studies on mice have shown that activation of androgen receptors by dihydrotestosterone in the brains of the tested animals led to the development of IR, whereas rodents deprived of these receptors did not develop this type of disorder