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SURMOUNT-1 results (72 weeks, adults with obesity): 5 mg dose: approximately 15% body weight loss 10 mg dose: 19.5% body weight loss 15 mg dose: 22.5% body weight loss Placebo: 3.1% body weight loss At the 15 mg maximum dose, the average participant lost about 52 pounds over 72 weeks
For broader quality context, our CJC-1295/Ipamorelin vs HGH guide explains why secretagogue research is different from exogenous growth hormone research, and our research peptide safety guide covers contamination, COA, and vendor-screening risks
the compound has not been approved as a medicine, and its safety profile in the context of systemic medical use has not been characterized at that level of detail
therefore, Life Extension currently recommends short-term use of berberine
The two work through different mechanisms and may produce additive benefits
