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In septic ICU patients with elevated lactate, treatment with vitamin C and thiamine lowered hospital mortality, showing the strongest benefit when both were given together, especially in vasopressor-dependent cases (Marik et al., 2017)

CAS Strategic Priority Research Program (XDB37030103 to HEX)

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Tirichen H, Yaigoub H, Xu W et al (2021) Mitochondrial reactive oxygen species and their contribution in chronic kidney disease progression through oxidative stress