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Membranes were pretreated with 5% non-fat milk/TBST (1 h) before overnight exposure at 4 C to antibodies targeting MAPKAPK2 (ab32567), HO-1 (ab189491), KEAP1 (ab119403), Nrf2 (ab137550), -H2AX (ab81299), PARP-1 (ab191217), CHK2 (ab207446), phosphorylated CHK2 (p-CHK2, ab59408), TYR (ab170905), PMEL (ab137078), MITF (ab12039), p-HSP27 (ab155987), HSP27 (ab12351), -actin (ab8226), and Histone H3 (ab1791) (all from Abcam, UK)

Setor K

Reducing cell damage in liver disease Hepatitis, alcohol abuse, and fatty liver disease all damage the cells of the liver

Huang S, Zhang Y, Wang L, et al

Some specialized medical diets like those used to treat certain metabolic disorders, including phenylketonuria, homocystinuria, and maple syrup urine disease, need to be supplemented with selenium to ensure optimal selenium status in patients (51)