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Low GH and normal/high IGF-I Obesity is a common yet serious condition associated with blunted spontaneous and stimulated GH secretion (87, 88), i.e., a state of relative GHD

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Association of hyperhomocysteinemia and chronic kidney disease in the general population: a systematic review and meta-analysis

Side effects arising from this direct receptor activation most notably the pronounced appetite stimulation that distinguishes GHRP-6 from other GHRPs are not mediated by GH and cannot be attributed to IGF-1 elevation

So it wasn't that we had some 60 or 70 year old who wasn't making enough insulin