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Kolterman OG, Gray RS, Griffin J, Burstein P, Insel J, Scarlett JA, et al

Contrave carries an FDA boxed warning about an increased risk of suicidal thoughts and behavior associated with its bupropion component

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It plays an important role in the defense mechanism against oxidative damage in erthrocytes by catalyzing the reduction of H 2 O 2 and variety of lipid hydro-peroxides [92] using GSH as the reducing substrate