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However, in a recent study on the inhibition of Hepa1-6 cell proliferation induced by oxidative stress, we found that increased expression of GPX6 protein may play a role in inhibiting oxidative stress (Tan et al., 2022)

doi: 10.1210/jc.2015-1966 164 Utz-MelereMTarga-FerreiraCLessa-HortaBEpifanioMMouzakiMMattosAA

These alterations may be further exacerbated by oxidative stress and activation of profibrotic cytokines, such as transforming growth factor , ultimately contributing to the development of chronic kidney disease (82)

Hamad, A.F., et al

(download TIF Changes in metabolites belonged to amino acids, peptides and analogues