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The textbooks describe a clear hierarchy of approaches: Steps that begin with general dental care: Prompt biopsy of any suspicious pigmented oral lesion, with histopathological examination and immunohistochemistry (S-100, HMB-45, SOX10, MART-1) to confirm the diagnosis

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These findings add evidence to the ability of curcumin to increase glutathione levels and protect cells from further oxidative stress and damage