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Gene expression modulation influences thousands of genes related to growth, repair, and metabolic regulation
Metabolomic analysis of PC12 cells, using ultra-performance liquid chromatography-quadrupole-time-of-flight mass spectrometry (UPLC-Q/TOF-MS), reveals that catalpol reverses an imbalanced metabolic state by regulating amino acid neurotransmitters, modulating amino acid and energy metabolism, and restoring oxidized substance levels, thus exerting neuroprotective effects (Zhang B
*Correspondence: Linlin Hao, [email protected] This article was submitted to Signaling, a section of the journal Frontiers in Cell and Developmental Biology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
