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3.2 ICH pathophysiology Primary brain injury (PBI) occurs when mechanical damage to blood vessels causes blood to flow into the brain parenchyma, forming a hematoma that compresses the surrounding brain tissue
Similarly, in HD, mHTT not only impairs autophagy initiation and mitochondrial trafficking, but also directly inhibits the TIM23 protein import complex, reducing the import of nuclear-encoded mitochondrial proteins and causing early mitochondrial dysfunction and oxidative stress [68, 69]
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A knowledgeable surgeon can help you understand the current evidence, potential risks, and evidence-based alternatives such as PRP (platelet-rich plasma) or other biologic treatments that have established clinical support.
Uridine and glutathione levels in the aqueous humor of POAG patients also tended to decrease from stage 1 and became significantly lower in stage 2 and 3 when compared to controls (Fig
