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The transition from animal wound healing to human wound healing applications has not been systematically pursued in clinical trials, despite the preclinical evidence

The usual dosage for initially treating vitamin B12 deficiency in older adults is 1000 micrograms, which can be given as a weekly intramuscular injection, or as a daily oral B12 supplement

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The SAR analysis revealed that an aspartyl residue at the S 2 position was superior for inhibitory efficacy compared to succinyl and glutamyl moieties

Important caveat: This combination has not been studied in controlled clinical trials