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Statins tackle cholesterol

These benefits can help create a healthier internal environment for gradual and sustainable weight management

doi: 10.1152/ajpendo.00551.2012 32 RoedSNWismannPUnderwoodCRKulahinNIversenHCappelenKAet al

Incretins help increase insulin production when needed and reduce the liver's sugar production when not required

FFA2 is activated predominantly by propionate and FFA3 by butyrate [EC 50 for acetate, propionate and butyrate at FFA2 are 431, 290 and 371 M respectively, and at FFA3 393, 41 and 33 M ( The gut microbiome is altered in obesity and T2D, an effect known as dysbiosis, where the ratio of the main bacterial phyla ( Firmicutes and Bacteroidetes ) becomes imbalanced, reducing diversity while the relative abundance of certain bacteria, including opportunistic pathogens, increases (Larsen et al., 2010)