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Some GLP-1 medications have demonstrated cardiovascular benefits in clinical trials (such as LEADER for liraglutide, SUSTAIN-6 for semaglutide, and REWIND for dulaglutide), and discontinuation may result in loss of these protective effects

Soares MP, Teixeira L, Moita LF (2017) Disease tolerance and immunity in host protection against infection

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Currently, some GLP-1 medications are only FDA-approved to manage blood sugar levels or reduce cardiovascular risk in people with type 2 diabetes, like Ozempic and Mounjaro