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Analysis of safety and pharmacodynamics of SANA in human volunteers Based on all the accumulated preclinical evidence supporting that SANA might be a suitable first-in-class drug for treatment of obesity and comorbidities, we performed a randomized, double-blind, placebo-controlled phase 1A/B clinical trial in healthy lean volunteers and in volunteers with obesity

Salt stress In plants, salinity stress leads to cellular dehydration, which enhances the production of ROS causing oxidative stress and thereby leading to enhanced expression of ROS scavenging enzymes