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N Engl J Med [internet] 379(23):22372245

In contrast, Retatrutide functions as a triple agonist, incorporating glucagon receptor activation alongside GLP-1 and GIP

Manufacturers are required to report these events while providers and patients are also given the option (but are not required) to report adverse events

Below is a side-by-side comparison: The Glucagon receptor in Retatrutide may push the body to increase its energy expenditure, which Tirzepatide does not directly address

These analyses used retrospective medical databases that did not include relevant nuances like a patient's comorbidities, or their exercise or eating habits, for example, says Dr