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The risk of liver fibrosis and cirrhosis was estimated by the AST to Platelet Ratio Index (APRI) score, calculated according to the following formula: [(AST/upper normal value] 100]/number of platelets

There is another phenomenon at play here - Demand curve is inelastic in short period and elastic over longer period, which mean falls in price is likely to increase demand over the next couple of years

Women using oral contraceptives should use a non-oral method or add a backup method for 4 weeks after initiating tirzepatide and for 4 weeks after each dose increase due to potential reduced contraceptive effectiveness

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Ben-Shachar, M., Ldecke, D., Makowski, D