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Limiting costs While insurance companies get a bad reputation for limiting access to patients, Novo Nordisk may also need to share blame for the high cost, Gostin said

In that scenario, succinate supplement could be beneficial, reestablishing directionality of the TCA cycle, supporting the electron transport chain and forcing the T cell into a more tolerant state

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These can help preserve both muscle and bone mass

Some patients may need levothyroxine dose adjustments as they lose weight, as thyroid hormone dosing is partially weight-based