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Apoyo a la desintoxicacin heptica En el hgado, el glutation cumple un rol esencial: une y neutraliza sustancias txicas para facilitar su eliminacin

10.1097/01.wcb.0000073905.87928.6d J

Studies have shown that chronic hyperglycemic diets increase the risk of colon cancer, in part by regulating the insulin/IGF-1 signaling axis by activating the downstream PI3K/AKT/mTOR, Ras/MAPK signaling pathways, glucose transporter proteins (GLUT1) and key enzymes of glycolysis (LDHA and HK2), thereby affecting glucose uptake and aerobic glycolysis in cancer cells (65)

Although the enzymes of the pathway are found at multiple locations within the cell, there is as yet little convincing evidence that they operate in the apoplastic space (Foyer and Kunert 2024)

Ansari MJ, et al