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Before prescribing and throughout treatment, healthcare providers should: Review current nutrition habits Educate adolescents and families about healthful nutrition intake Emphasize regular meals with adequate protein despite loss of appetite Ensure adequate water intake It's also crucial to assess emotional health and the possibility of disordered eating before starting any obesity treatment, including medication

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For pure weight-loss endpoints, retatrutide outperforms semaglutide by roughly 9 percentage points at peak dose: 24.2% versus ~15% mean body-weight loss at comparable durations [3][4]

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