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In mouse models of glioblastoma, MMP-9 secreted by F4/80 + macrophages triggered the local activation of sequestered VEGF bound to the ECM, making it available for binding to VEGFR2 and leading to endothelial cell activation (48)

Perike, A

This activation triggers downstream signaling pathways, leading to the phosphorylation of STAT proteins, thereby regulating the expression of a series of genes and affecting cell function and physiological activity

137 Observational data suggest an inverse relationship between serum levels of ascorbic acid and blood levels of lead

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