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Erythrophagocytosis by liver macrophages (Kupffer cells) promotes oxidative stress, inflammation, and fibrosis in a rabbit model of steatohepatitis: implications for the pathogenesis of human nonalcoholic steatohepatitis
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In Lox homozygous null models ( Lox -/- ), the activity of LOX was reduced by up to 80%, and the phenotype of the lungs resembles those of patients with emphysema and dilated distal airways
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