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P., Stanley, T., Grinspoon, S., Falutz, J., Mamputu, J.-C., Marsolais, C., McComsey, G

Accumulating clinical evidence indicates that GLP-1RAs mediate their cardioprotective actions largely via metabolic reprogramming (75, 76)

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J Clin Med (2023) 12(5):1858

This has been confirmed in meta-analyses of tens of clinical trials concerning statins published in the last few years which demonstrated a significant reduction in Alzheimers dementia, vascular dementia, and generally mild cognitive impairment with statin use [376, 377], of which pleiotropic properties of this class of agents are supposed to be the cause