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The percentage of patients who responded to treatment increased from 34% to nearly 39% after one year (Rotaru et al., 2020)
However, the precise role of CD26 in T cells and other immune cells as well as the precise signaling pathway involved have not as yet been elucidated
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These analgesic properties position DSIP as valuable research compound for developing non-opioid pain management strategies, understanding the relationship between sleep and pain processing, and investigating peptide-based approaches to chronic pain treatment
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