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The meta-analysis by Cheng et al

To learn more about the benefits, risks, & differences of compounded medication substitutes you may visit the FDA Drug Shortage List & FDA Compounding Substitutions Information Page

95% CI, 0.82-2.51) were reported more often in women at high risk for developing breast cancer who received 5 years of tamoxifen therapy (n = 6681) compared with placebo (n = 6707)

Important safety considerations include potential side effects such as nausea, vomiting and diarrhoea