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Overall, phytochemicals and botanicals offer mechanistic plausibility and early clinical signals but lack the robust evidence base seen with micronutrients like selenium

Unlike phosphodiesterase-5-targeted research compounds, PT-141 operates through a centrally mediated mechanism rather than peripheral vascular pathways

"This berberine supplement helped me improve my fasting glucose values assessed three months apart

Acknowledgements The authors acknowledge the support of grants from the National Key Research and Development Program of China (grant no