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Brighten: of McCall McPhereson: semaglutide

See our guide on what happens if tirzepatide gets warm for general guidance on temperature excursions

2011 Jan 11;31(5):595605

MHRA approves first dual GIP and GLP-1 receptor agonist Mounjaro (tirzepatide) for weight management

Decision factors: Weight loss goals: Want maximum weight loss and can tolerate side effects: Tirzepatide (Zepbound) shows ~4% greater weight loss than semaglutide on average Want proven cardiovascular benefits: Semaglutide has demonstrated 20% reduction in major cardiovascular events in the SELECT trial Want to try oral option: Oral semaglutide (Rybelsus) for diabetes, though weight loss is less than injectable Side effect sensitivity: Some people tolerate one better than the other