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Moreover, use of dulaglutide in people with T2DM is likely to confer additional renal benefits, and dulaglutide may be used in advanced chronic kidney disease at any eGFR level and without dose adjustment in contrast with most other noninsulin diabetes therapies (134, 135)

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H(2)S protects against pressure overload-induced heart failure via upregulation of endothelial nitric oxide synthase