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To use the language of diet book doctors, the drug makes the body shift into a fat-burning mode (as shown by the drop in RER), which then: Feeds the system from within, making the stored fat available for oxidation, which Suppresses appetite indirectly, and Attenuates the usual energy-conserving adaptations that go with calorie-restricted diets and weight loss

For patients with diabetes, intensified glucose monitoring is crucial after discontinuation

What are the main vision problems associated with GLP-1 drugs

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