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Every vial is sealed according to pharmaceutical manufacturing standards and tested for sterility before distribution

Naunyn-Schmiedebergs Arch Pharmacol 385:953959

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Studies have used MT-II in direct comparison with MT-1 to characterise how cyclisation of the -MSH pharmacophore core changes receptor subtype selectivity , establishing that constraining the heptapeptide into a cyclic conformation shifts selectivity toward MC3R/MC4R relative to the linear tridecapeptide that preferentially activates MC1R

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