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Much of what is sold online is labeled research only, and the purity of those products is highly variable, with independent testing repeatedly finding under-dosed, degraded, or mislabeled peptides across the unregulated market
Because of that, the NICE recommendations lean towards individualised care: tailoring the dose, frequency and delivery method, following people up at around three months, and reviewing sooner if symptoms are severe or if someone is pregnant or breastfeeding
The article on why not losing weight on semaglutide discusses multiple factors that affect results, including peptide quality
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