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The multifunctional Au@miR-183i nanocomplexes (NCs) are engineered to self-assemble in the TME, disrupting redox homeostasis by depleting NADPH and HO, resulting in increased ROS levels, modulation of the LCSC niche, and diminished cancer cell stemness

This is not accounted by antipsychotic exposure and the two neurotransmitters systems are known to be associated in the striatum

Studies have found that the reduction of AMPK activity is an important pathological feature of NAFLD, and targeted activation of the AMPK signaling pathway can significantly improve liver lipid metabolism disorders and related pathological injuries (Figure 3)

doi: 10.1016/j.bpg.2025.102064 96 IsmailYLeeHRiordanSMGrimmMCZhangL

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