It isn't, in this disease, ever
Its core biology is well characterized and elegant: T4 is the major intracellular actin-sequestering protein, and when released after injury it moonlights extracellularly as a repair signal, promoting cell migration, angiogenesis, and reduced inflammation and scarring
Glucose control The SURPASS studies enrolled populations that were similar in terms of baseline HbA1c levels, which ranged from 7.9 to 8.5% [2, 3, 59,60,61] and found a statistically significant reduction in HbA1c already at the 5 mg dose, demonstrating a greater efficacy of tirzepatide compared to placebo or active comparator [2, 3, 59,60,61]
Kim S, Cho MC, Cho SY, Chung H, Rajasekaran MR
Its most important known metabolic function is to transport long-chain fatty acids to the mitochondria of muscle cells, where they are oxidized to produce energy