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This cross-reactive detection can break immune tolerance and initiate or amplify an inflammatory cascade against the islets of Langerhans

doi:10.1016/j.jad.2010.12.019, PMID: 21277635 Maes M, Van de Vyvere J, Vandoolaeghe E, Bril T, Demedts P, Wauters A, Neels H (1996) Alterations in iron metabolism and the erythron in major depression: further evidence for a chronic inflammatory process

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