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As noted by Mahiques-Santos, the higher incidence of side effects associated with MT-II is due to its being less receptor-specific than MT-I [1]

While GLP-1 agonists excel in A1C reduction and weight loss, SGLT2 inhibitors provide powerful heart and kidney protection, making them particularly valuable for patients with related health concerns

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Ramos KC, Macas MDPC

Volman V, Behrens MM, Sejnowski TJ