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Novo Nordisk cited concerns about Hims & Hers selling and promoting knockoff compounded GLP-1 drugs, which are more affordable versions of the popular weight loss medications

329,330 In degenerative joint diseases like OA, the metabolic balance of chondrocytes is disrupted, leading to the overproduction of degrading enzymes and inflammatory mediators, including iNOS, MMP-13, and ADAMTS5 (a disintegrin and metalloproteinase with thrombospondin motifs 5), which participate in cartilage degradation and inflammatory processes

In February 2025, the National Medical Products Administration (NMPA) approved Innogens ultra-long-acting GLP-1 injection for type 2 diabetes, signaling growing government and regulatory support for GLP-1 innovation and boosting industry confidence

Tanaka Y, Iwaya C, Kawanami T, Hamaguchi Y, Horikawa T, Shigeoka T, et al