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Cytokine production and response are important as they participate in immune and inflammatory responses
GHK-Cu acts on surface regeneration (collagen, elastin, gene expression, skin anti-aging)
Since a Cul3 haploinsufficient mouse model also showed an upregulation of RhoA expression, treatment using the RhoA inhibitor Rhosin was used to successfully rescue these phenotypes in vitro in primary cortical neuron cultures derived from these mice [34]
