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Goal: Reduce visceral (deep abdominal) adipose tissue and improve lipid profiles through sustained GH/IGF-1 elevation [3] [4]

Researchers and athletes often explore this combination because it may support muscle growth, fat metabolism, recovery, and overall body composition

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M1 macrophages are pro-inflammatory, useful in the very early stages of healing for clearing debris but destructive if they persist

Study designs in this population often measure changes in visceral fat and lean mass together, given that male physiology tends to show a closer relationship between growth-hormone signaling and both outcomes