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Association of genetic variants related to CETP inhibitors and statins with lipoprotein levels and cardiovascular risk

GSH constrains NLRP3 activation primarily by scavenging H 2 O 2 and preserving mitochondrial redox balance

Risks were lower across every major substance examined, including alcohol (18%), cannabis (14%), cocaine (20%), nicotine (20%), and opioids (25%)

However, effective pharmacotherapeutic options remain limited

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