The robust growth was driven by expanded use in both early and advanced breast cancer settings, particularly following its approval for adjuvant treatment in high-risk early-stage patients
Wegovy: EPAR Medicine Overview
Meanwhile, GLP-1s such as Ozempic (semaglutide) and Trulicity (dulaglutide) are very effective at managing post-meal blood sugars, have a low risk of hypoglycemia, and help with weight loss
Activated astrocytes can shift toward different phenotypes: the A1 type, induced via NF-B signaling, produces proinflammatory mediators and can trigger neuronal apoptosis, whereas the A2 phenotype, driven by STAT3 activation, promotes anti-inflammatory and neuroprotective responses [32]
Additionally, certain GLP-1 agonists might be unsuitable for chronic gastroparesis patients or people suffering from chronic kidney disease