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Virtas prior clinical trials and real-world outcomes showed significant and sustained weight loss through a medication-free approach, demonstrating members who never started on GLP-1s were able to achieve and sustain similar weight loss to those who received GLP-1 therapy

ESSENCE Phase 3 semaglutide in MASH data supported FDA approval in March 2024 , creating a premium pricing tier in a disease category with USD 17.4 billion addressable market and no prior approved pharmacotherapy

These data, together with our findings, suggest that dose adjustment of CagriSema is unlikely to be needed in people with renal or hepatic impairment

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