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And What About Glycolic Acid

Additionally, more than 70% of DFU patients will ultimately require lower limb amputation, imposing a heavy financial burden and severe impairment to patients quality of life [160]

Taken weekly, premium GLP-1 is the active ingredient in medicines used to treat type 2 diabetes and treat obesity

To address this limitation, research has concentrated on many strategies, including identifying and developing DPP-IV inhibitors 43,44 , altering the structural makeup of GLP-1, searching for structural analogues that are more resistant to DPP-IV cleavage 45 , and increasing its hydrodynamic radius ( R h) above the glomerular filtration cutoff by conjugating it to proteins such as transferrin 46 , albumin 47 , and elastin-like polypeptides 48

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