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IS: Investigation, Methodology, Writing original draft

Central Nervous System Effects Study Type: fMRI brain imaging study Key Finding: Cagrilintide activates amylin receptor-rich regions in the area postrema and nucleus tractus solitarius, distinct from GLP-1R activation patterns

MT-1's aromatic amino acids (phenylalanine, tyrosine) are photosensitive, meaning UV and visible light cause structural changes that reduce receptor binding affinity