Excess fat may activate the sympathetic nervous system (SNS), increasing heart rate and causing other cardiovascular changes which contribute to high blood pressure
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ROS sources ROS are unstable oxygen-containing molecules that include radical ROS (e.g., superoxide anions [O 2 ], hydroxyl radicals [OH], peroxyl radical [ROO], alkoxyl radical [RO], carbonate radical [CO 3 ], hydroperoxyl radical [HO 2 ], nitric oxide [NO], and nitrogen dioxide [NO 2 ]) and non-radical ROS (e.g., hydrogen peroxide [H 2 O 2 ], peroxynitrite [ONOO ], hypochlorous acid [HOCl], singlet oxygen [ 1 O 2 ], ozone [O 3 ], and nitrocarbonate [ONOOCO 2 ]) [11] (Table 1)
While genetic variants don't predict exact medication response, they may indicate whether you're sensitive to minor potency reductions from storage or formulation variation
Statistical analysis Statistical analyses were performed using IBM SPSS Statistics software
