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This universal conjunction, mediated by the IgG Fc region, can trap both viruses and bacteria in all major mucosal secretions 74

J Immunol Baltim Md 184:965974 Zheng S, Yang J, Hu X, Li M, Wang Q, Dancer RCA, Parekh D, Gao-Smith F, Thickett DR, Jin S (2020) Vitamin D attenuates lung injury via stimulating epithelial repair, reducing epithelial cell apoptosis and inhibits TGF- induced epithelial to mesenchymal transition

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In KCs, SIRT1 deacetylates the NF-B p65 subunit, inhibiting its transcriptional activity and reducing the expression of pro-inflammatory cytokines such as TNF-, IL-1, and IL-6