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Clinical trials demonstrate HbA1c reductions of 0.8-1.0% from baseline, with greater reductions observed in patients with higher baseline HbA1c levels

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Unused sign or exponent bits from the floating-point representation are therefore avoided, and some of the trailing mantissa bits are discarded in quantization

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Hit all three and the lean-mass cost drops sharply

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Trapp S, Richards JE

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