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Activation of the Wnt/-catenin signaling pathway is important for the initiation and maintenance of hair morphogenesis 29,38 , and is critical for the maintenance of DPC-inductive properties required for hair-follicle regeneration and growth of the hair shaft 39,40

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6.1 Osteocalcin as an endocrine regulator of metabolism Osteocalcin is the most extensively studied endocrine peptide derived from bone

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It is noteworthy that a recent large-scale real-world study based on the FDA Adverse Event Reporting System revealed that Regadenoson may induce neurological and urinary adverse effects not listed in its prescribing information, in addition to known reactions such as chest pain and dyspnea (38)