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Intriguingly, correlation analyses linked microbiota changes to alterations in stress hormones, neurotransmitters, inflammatory markers and anxiety-like behaviors, suggesting a gutbrain contribution to the observed behavioral manifestations in anxiety pathology (Jia et al., 2024

As outlined above, pramlintide treatment is associated with 2%6% reductions in body weight across several patient categories, including individuals with obesity and type 2 diabetes, who are prone to develop hepatic steatosis

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However, it remains unresolved whether the anti-inflammatory effects are direct or simply reflect the weight losses

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