Its a unique amino acid because its not used to form proteins, unlike many other amino acids (such as l-carnitine, leucine, lysine, methionine or tryptophan), and is not used to make enzymes
f , Dose-dependent toxicity of RSL3 in a panel of genetically modified (mouse (mFSP1) and human (hFSP1) FSP1 overexpression) human cancer cell lines (IMR5/75 mock, IMR5/75 hFSP1, 786-O mock, 786-O hFSP1, LOX-IMVI mock, LOX-IMVI hFSP1, HLF mock, HLF hFSP1, U-138 mock and U-138 mFSP1) treated with or without iFSP1 and Lip-1
Clinical trials ran for 12 weeks without safety concerns
This work was also supported by the Rural & Environment Science & Analytical Services (RESAS) Division of the Scottish Government through project JHI-B1-1, the Biotechnology and Biological Sciences Research Council (BBSRC) through award BB/S015663/1
Zealand Pharma is another important name because of licensing activity around survodutide